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Modified GRF (1-29)



Modified GRF (1-29)

Modified GRF (1-29) often abbreviated as mod GRF (1-29), originally known as tetrasubstitued GRF (1-29).

Sometimes referred to as CJC-1295 without DAC, it is categorized as a growth hormone secretagogue, a compound which stimulates increased secretion of growth hormone from the pituitary gland. Although similar to Sermorelin, Mod-GRF has four amino acid substitutions made to its chemical structure, hence the alternate name “tetrasubstituted” GRF 1-29. These changes effectively increase the stability of Mod GRF during storage, transportation, and administration while enhancing its affinity for the GHRH receptor.

The presence of lysine in a literal “CJC without DAC” in the absence of MPA would have the opposite effect of DAC: it would drastically reduce the active life of the peptide to that of Sermorelin. Modified GRF (1-29) is the same as CJC-1295 with out DAC.



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